engleski

Fibre intake as a tool for manipulating gut microbiota ina n obese individual

Microbiota plays an increasingly important role for the wellbeing of the host. It has been correlated with a plethora of conditions, raging form gastrointestinal to immunological and metabolic diseases. It is believed microbiota plays an important role in the onset, development, and treatment of obesity, with the exact mechanisms still unclear. Diet is one of the major factors affecting the microbiota - especially the intake of dietary fibres (prebiotics), which is believed to positively affect the microbiota composition. We had tested the concept of modulating the microbiota composition using prebiotics in a physically active obese male. Dietary intake and fibre intake were assessed before the intervention, using a food frequency questionnaire. The intervention consisted of daily supplementation with the commercial prebiotic Nutriose® until the maximum daily intake of fibre was achieved. No major change of dietary style, calorie intake, and lifestyle was recommended. The intervention was carried out for 30 days, and body height, weight, and composition were measured, and stool samples were taken at the beginning, after 15 days, and after 30 days of intervention. Anthropometric parameters showed a 5% decrease of body weight with a significant reduction of body fat (12.2%) and a decrease in visceral fat from 15 to 13. Microbiota composition showed a significant increase of

microbiota ; obesity ; prebiotics ; dietary supplements

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