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CLINOPODIUM VULGARE L. ESSENTIAL OIL – CHEMICAL COMPOSITION, CHOLINESTERASE INHIBITION AND ANTIOXIDANT POTENTIAL (CROSBI ID 680309)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Mejra Bektašević, Olivera Politeo, Ivana Carev CLINOPODIUM VULGARE L. ESSENTIAL OIL – CHEMICAL COMPOSITION, CHOLINESTERASE INHIBITION AND ANTIOXIDANT POTENTIAL // Book of Abstract / Novak, Johaness. Stappen, Iris (ur.). Beč, 2019. str. 102-102

Podaci o odgovornosti

Mejra Bektašević, Olivera Politeo, Ivana Carev

engleski

CLINOPODIUM VULGARE L. ESSENTIAL OIL – CHEMICAL COMPOSITION, CHOLINESTERASE INHIBITION AND ANTIOXIDANT POTENTIAL

Clinopodium vulgare L. (Lamiaceae) is medicinal plant characteristic for traditional medicine of Bosnia and Herzegovina (BiH). In BiH Clinopodium vulgare L. is used in the treatment of digestive disorders [1], while in traditional medicine of other countries this plant is used for treatment of diabetes, cancer and viral skin diseases [2, 3]. Medicinal plants are rich in bioactive compounds. Oxidative stress is related with etiology and pathogenesis of many chronic diseases and bioactive antioxidant compounds may have an important role in their prevention and treatment. Ihibitors of cholinesterase have important role in the treatment of Alzheimer’s disease and many components of essential oils and plants extracts are being tested as potential cholinesterase inhibitors. In this work chemical composition of Clinopodium vulgare L. essential oil, from the area of BiH, is determined using GC/MS and GC/FID technique. Inhibition of acetylcholinesterase and butyrylcholinesterase was tested by Ellman’s method [4], while antioxidant potential was tested using DPPH and FRAP method. The results of the analysis of essential oil showed that analyzed oil is rich in sesquiterpenes. The major compounds were epi-bicyclosesquiphelandrene (18.1%), α-gurjunene (10.9%) and hexadecanoic acid (10.5%). Compared to standard compounds BHA and vitamin C, Clinopodium vulgare L. essential oil showed moderate antioxidative potential, as well as moderate ability to inhibit the enzymes acetylcholinesterase (40%) and butyrylcholinesterase (23%) in concentration of 1 g/L in stock solution.

Clinopodium vulgare L., essential oil, antioxidant activity, cholinesterase inhibition

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Podaci o prilogu

102-102.

2019.

objavljeno

Podaci o matičnoj publikaciji

Book of Abstract

Novak, Johaness. Stappen, Iris

Beč:

Podaci o skupu

50th International Symposium on Essential Oils

poster

09.09.2019-11.09.2019

Beč, Austrija

Povezanost rada

Kemija