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Pregled bibliografske jedinice broj: 1011795

Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia


Srsen, Sasa; Frkovic Marijan; Metlicic, Vitomir; Stricevic, Luka; Pecnjak, Marija; Held, Martina; Jelusic, Marija
Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia // Pediatr Rheumatol Online J
Atena, Grčka, 2017. str. /-/ (poster, međunarodna recenzija, prošireni sažetak, znanstveni)


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Naslov
Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia

Autori
Srsen, Sasa ; Frkovic Marijan ; Metlicic, Vitomir ; Stricevic, Luka ; Pecnjak, Marija ; Held, Martina ; Jelusic, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, prošireni sažetak, znanstveni

Izvornik
Pediatr Rheumatol Online J / - , 2017, /-/

Skup
The 24th Paediatric Rheumatology European Society Congress

Mjesto i datum
Atena, Grčka, 14-17.09.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Henoch-Schonlein purpura ; nephritis ; epidemiology

Sažetak
Objectives: To compare characteristics of paediatric patients with IgA vasculitis treated in two tertiary centres in different parts of Croatia: Split (Mediterranean part of Croatia) and Zagreb (continental part of Croatia) during ten years period. Methods: Historical chart review of patients treated in University Hospitals in Split and Zagreb from 2006 until 2015. Results: During observed period of time 160 children were treated due to IgA vasculitis in University Hospital Zagreb (81 boy and 79 girls), and 135 in University Hospital Split (66 boys and 69 girls). Most of the patients had a monophasic disease (129 in Zagreb and 120 in Split), 23 patients in Zagreb and 11 in Split had one relapse of disease, 6 patients in Zagreb and 4 in Split had two relapses, while 2 patients in Zagreb had three relapses of the disease. The largest number of patients was between 3 and 8 years old with a peak number of patients at the age of 4. Mean age of patients (average +/- standard deviation) was 6.68+/-3.01 in Zagreb and 7.11+/-3.86 in Split. A number of patients treated per year were between 11 and 24 in Zagreb and 10 and 20 in Split. The peak incidence of IgA vasculitis was observed in February and October in Zagreb (26 and 25 patients), but with a stable number of patients from August until June. In Split peak incidence was in November (23 patients) with a predominance of disease in the period from October until February and lower number of patients in rest of the year. All of the patients in both centres presented with a characteristic rash. In Zagreb 62.7% of patients had arthritis, 33.1% gastrointestinal involvement, 17.5% renal involvement and 4.7% of boys had affected scrotum, while in Split those numbers were 68.9%, 32.4%, 8.6% and 8.1% in the same order. 15 patients with renal involvement in Zagreb underwent renal biopsy and 9 of them had IgA nephritis (5 subclass II according to Haas and 4 subclass III). 8 patients in Split underwent renal biopsy. 1 of them had IgA nephritis subclass I, II and V according to Haas, 3 had subclass III and 1 had subclass IV. Rash was most often present on legs (98.8% in Zagreb, 100% in Split), buttocks (52.7% in Zagreb, 59.7% in Split) and arms (31.7% in Zagreb, 31.5% in Split), while it was more seldom on trunk (10.2% in Zagreb, 10.7% in Split) and face (6.5% in Zagreb, 5.4% in Split). IgA vasculitis was preceded by infection in 59.4% of patients in Zagreb and 58.3% in Split, most often respiratory tract infection (47.5% of patients in Zagreb, 49% in Split), while other (gastrointestinal tract, urinary tract and other) were seldom. Most often isolated cause of infection was beta- hemolytic streptococcus in Zagreb and Streptococcus pneumoniae in Split. Antistreptolysin O titer was positive in 29.1% of patients in Zagreb and 52.6% of patients in Split. The largest number of patients in Zagreb was treated with non-steroid anti-inflammatory drugs (NSAID) (50.6%), 45% were treated with corticosteroids, and 1.9% of patients with immunosuppressives, while in Split 32% of patients were treated with corticosteroids, 28.8% with NSAID and 2.9% with immunosuppressives. Conclusion: Patients with IgA vasculitis treated in two tertiary centres in Croatia, one in Mediterranean and one in continental region, had similar characteristics. We noticed more often the appearance of the disease in autumn and winter in the Mediterranean part of Croatia, while in continental although there were more patients in autumn and winter, a number of patients was stable during the whole year. There were fewer patients with renal involvement than expected in Mediterranean area.

Izvorni jezik
Engleski

Napomena
Sažetak objavljen u časopisu Pediatr Rheumatol Online J. 2017 ; 15(Suppl 2): 65, koji je zastupljen u Current contentsu (CC)



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb

Profili:

Avatar Url Martina Held (autor)

Avatar Url Marija Jelušić (autor)

Citiraj ovu publikaciju

Srsen, Sasa; Frkovic Marijan; Metlicic, Vitomir; Stricevic, Luka; Pecnjak, Marija; Held, Martina; Jelusic, Marija
Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia // Pediatr Rheumatol Online J
Atena, Grčka, 2017. str. /-/ (poster, međunarodna recenzija, prošireni sažetak, znanstveni)
Srsen, S., Frkovic Marijan, Metlicic, V., Stricevic, L., Pecnjak, M., Held, M. & Jelusic, M. (2017) Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia. U: Pediatr Rheumatol Online J.
@article{article, year = {2017}, pages = {/-/}, keywords = {Henoch-Schonlein purpura, nephritis, epidemiology}, title = {Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia}, keyword = {Henoch-Schonlein purpura, nephritis, epidemiology}, publisherplace = {Atena, Gr\v{c}ka} }
@article{article, year = {2017}, pages = {/-/}, keywords = {Henoch-Schonlein purpura, nephritis, epidemiology}, title = {Comparison of patients with iga vasculitis in Mediterranean and continental part of Croatia}, keyword = {Henoch-Schonlein purpura, nephritis, epidemiology}, publisherplace = {Atena, Gr\v{c}ka} }




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