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Pregled bibliografske jedinice broj: 1009012

Antithrombotic activity of flavonoids and polyphenols rich plant species


Bojić, Mirza; Maleš, Željan; Antolić, Andrea; Babić, Ivana; Tomičić, Maja
Antithrombotic activity of flavonoids and polyphenols rich plant species // Acta pharmaceutica, 69 (2019), 4; 483-495 doi:10.2478/acph-2019-0050 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1009012 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Antithrombotic activity of flavonoids and polyphenols rich plant species

Autori
Bojić, Mirza ; Maleš, Željan ; Antolić, Andrea ; Babić, Ivana ; Tomičić, Maja

Izvornik
Acta pharmaceutica (1330-0075) 69 (2019), 4; 483-495

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
platelet aggregation, polyphenols, plant species, cardiovascular diseases

Sažetak
Cardiovascular diseases represent one of the most notable health problems of the modern civilization. Stroke and heart attack often lead to lethal outcome, and essential problem underneath being thrombus formation. Prophylactic approaches include acetylsalicylic acid and clopidogrel therapy on the level of primary hemostasis, i.e., primary clot formation. In the last five years, in the USA, health care expenses related to cardiovascular diseases have increased 50 %, to over 350 billion dollars. Thus, application of plant species and medicinal plants rich in polyphenols in prevention of thrombus formation are of interest. This is supported by the fact that the number of publications on antiaggregatory effect of polyphenols has doubled in the last decade. In this mini-review we focus on antiaggregatory effect of most abundant polyphenols – flavonoids, the effect of plant extracts rich in polyphenols (propolis, species Salvia sp., Calamintha nepeta L., Lavandula angustifolia Mill., Melissa officinalis L, Mentha x piperita L., Ocimum basilicum L., Origanum vulgare L., Rosmarinus officinalis L.) on platelet aggregation, association of chemical composition and antioxidant properties with the observed biological effect, and possible clinical significance of the published results.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Farmacija



POVEZANOST RADA


Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Hrvatski zavod za transfuzijsku medicinu

Profili:

Avatar Url Željan Maleš (autor)

Avatar Url Maja Tomičić (autor)

Avatar Url Mirza Bojić (autor)

Citiraj ovu publikaciju

Bojić, Mirza; Maleš, Željan; Antolić, Andrea; Babić, Ivana; Tomičić, Maja
Antithrombotic activity of flavonoids and polyphenols rich plant species // Acta pharmaceutica, 69 (2019), 4; 483-495 doi:10.2478/acph-2019-0050 (međunarodna recenzija, članak, znanstveni)
Bojić, M., Maleš, Ž., Antolić, A., Babić, I. & Tomičić, M. (2019) Antithrombotic activity of flavonoids and polyphenols rich plant species. Acta pharmaceutica, 69 (4), 483-495 doi:10.2478/acph-2019-0050.
@article{article, year = {2019}, pages = {483-495}, DOI = {10.2478/acph-2019-0050}, keywords = {platelet aggregation, polyphenols, plant species, cardiovascular diseases}, journal = {Acta pharmaceutica}, doi = {10.2478/acph-2019-0050}, volume = {69}, number = {4}, issn = {1330-0075}, title = {Antithrombotic activity of flavonoids and polyphenols rich plant species}, keyword = {platelet aggregation, polyphenols, plant species, cardiovascular diseases} }
@article{article, year = {2019}, pages = {483-495}, DOI = {10.2478/acph-2019-0050}, keywords = {platelet aggregation, polyphenols, plant species, cardiovascular diseases}, journal = {Acta pharmaceutica}, doi = {10.2478/acph-2019-0050}, volume = {69}, number = {4}, issn = {1330-0075}, title = {Antithrombotic activity of flavonoids and polyphenols rich plant species}, keyword = {platelet aggregation, polyphenols, plant species, cardiovascular diseases} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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