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Pregled bibliografske jedinice broj: 1007981

Mechanochemical Friedel–Crafts acylations


Đud, Mateja; Briš, Anamarija; Jušinski, Iva; Gracin, Davor; Margetić, Davor
Mechanochemical Friedel–Crafts acylations // Beilstein journal of organic chemistry, 15 (2019), 1313-1320 doi:10.3762/bjoc.15.130 (međunarodna recenzija, članak, znanstveni)


Naslov
Mechanochemical Friedel–Crafts acylations

Autori
Đud, Mateja ; Briš, Anamarija ; Jušinski, Iva ; Gracin, Davor ; Margetić, Davor

Izvornik
Beilstein journal of organic chemistry (1860-5397) 15 (2019); 1313-1320

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Ball milling ; Friedel–Crafts reaction ; mechanochemistry

Sažetak
Friedel–Crafts (FC) acylation reactions were exploited in the preparation of ketone- functionalized aromatics. Environmentally more friendly, solvent-free mechanochemical reaction conditions of this industrially important reaction were developed. Reaction parameters such as FC catalyst, time, ratio of reagents and milling support were studied to establish the optimal reaction conditions. The scope of the reaction was explored by employment of different aromatic hydrocarbons in conjunction with anhydrides and acylation reagents. It was shown that certain FC-reactive aromatics could be effectively functionalized by FC acylations carried out under ball-milling conditions without the presence of a solvent. The reaction mechanism was studied by in situ Raman and ex situ IR spectroscopy.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2013-11-9310 - Nekovalentne interakcije u dizajnu novih fotoosjetljivih molekula (Davor Margetić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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