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Effect of the mediterranean and standard hypolipemic diet on parameters of metabolic syndrome

The aim of this study was to explore the effect of Mediterranean diet (MD) and Standard hypolipemic diet (SHD) on parameters of metabolic syndrome in obese patients in a randomized controlled study.Methodology: 124 subjects with a body mass index (BMI) above 30 kg/m2 were recruited from the outpatient Clinic of Department of endocrinology, diabetes and metabolism disorders at Dubrava University Hospital in the period from November 2008 to February 2013, and were randomly assigned to either MD or Standard hypolipemic diet SHD. All subjects received education on their diet during one-week stay in Daily hospital. Parameters of metabolic syndrome (waist circumference, blood pressure, glucose level, triglycerides and HDL) were obtained at the baseline (day 1) and at each subsequent visit (after 7 days, 1, 3, 6 and 12 months). Data were entered into SPSS version 20.0 (SPSS Inc, Chicago, III) for analysis. Results: During 12 months period, significant decrease was observed for both diets, for waist circumference (mean decrease was 7.00 cm in MD group (P<0, 05) and 5, 65 cm in SHD group (P<0, 05)), and for glucose (mean decrease was 0, 52 mmol/L for both groups (P<0, 05)). Significant increase in the HDL cholesterol value of 7, 12% (P<0, 05) was induced by the MD group, whereas slight (3, 06%), though insignificant increase was observed by the SHD group. However, when comparing the two diets, significant difference was not found for any of the explored parameters. Conclusion: During 12 months period, both diets showed beneficial effects on waist circumference and glucose level. MD showed higher beneficial influence on HDL cholesterol than SHD what supported previous study results.

mediterranean diet ; hypolipemic diet ; metabolic syndrome

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