Chloride-Assisted Peptide Macrocyclization (CROSBI ID 277170)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Vidović, Nikolina ; Horvat, Gordan ; Riva, Davide ; Rinkovec, Tamara ; Cindro, Nikola ; Tomišić, Vladislav ; Speranza, Giovanna
engleski
Chloride-Assisted Peptide Macrocyclization
The role of the Cl– anion as a templating agent for the synthesis of cyclopeptides was assessed through the preparation of three new homocyclolysines and other six cyclic peptides by head-to-tail lactamization. Isolated yields of products obtained by chloride-templating approach were considerably higher than those gained by a cation-promoted procedure, whereby, in some cases, only the anion-assisted synthesis yielded the desired cyclopeptides.
Salts ; Anions ; Peptides ; Proteins ; Cyclization ; Titration
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Podaci o izdanju
Povezanost rada
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje), Kemija